No large-effect low-frequency coding variation found for myocardial infarction

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No large-effect low-frequency coding variation found for myocardial infarction.

Genome-wide association studies have identified variants, primarily common, that are associated with coronary artery disease or myocardial infarction (MI), but have not tested the majority of the low frequency and rare variation in the genome. We explored the hypothesis that previously untested low frequency (1-5% minor allele frequency) and rare (<1% minor allele frequency) coding variants are...

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Effect of Myocardial Infarction

a microprocessor system capable of averaging 256 QRS complexes to reduce noise. The QRS was digitally filtered and the root-mean-square (RMS) voltage of the residual (80-300 Hz) signal computed. High-frequency RMS values were significantly (p < 0.01) greater in leads II, III and aV7 in normal subjects (n = 12) than in patients with inferior infarction (n = 12). Similarly, high-frequency RMS val...

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Myocardial Infarction and No Residual Ischemia

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ژورنال

عنوان ژورنال: Human Molecular Genetics

سال: 2014

ISSN: 0964-6906,1460-2083

DOI: 10.1093/hmg/ddu175